少年时期在纽约开始舞台生涯，1910年在齐格菲舞台剧中展露才华，1928年步入影坛，其经历后被改编为电影《滑稽女郎》
During the early times of the Depression when life was more famine than feast, child stars became the blue plate special of the day, served up by Hollywood to help nourish a nation besieged with troubles. Following 20th Century-Fox monumental success with Shirley Temple in the early 1930s, every studio was out searching for its own precocious little commodity who could pack 'em in the aisles despite the lean times. While Paramount whipped up "Little" Mitzi Green, MGM offered Jackie Cooper in the hopes of finding a similar box office jingle. Wildly talented Janie Withers fit the bill, too, and although she earned pint-sized prominence just like the others, it was also for Temple's Fox Studios. As such, Jane remained somewhat of a side course to Temple's main dish (what child star didn't?) throughout much her young "B" level reign. Nevertheless, she became a major bright star in her own right.
